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6L) were significantly reduced in rod Igf-1r / mice compared with wild-type mice, suggesting that IGF-1R signaling regulates the cellular redox, which may further promote photoreceptor survival and function

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The mechanism by which GLP-1 receptor agonists might contribute to pancreatitis risk remains unclear, but possibilities include effects on pancreatic enzyme secretion, changes in gallbladder motility leading to gallstone formation, or direct effects on pancreatic tissue

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