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Results BSO synergistically enhanced L-PAM-induced cytotoxicity in nine MM cell lines, in presence of BMSC and MM cytokines, and in seven primary MM cells We determined the cytotoxicity of clinically achievable levels of BSO (0400 M) and L-PAM (050 M) in nine human MM cell lines using the DIMSCAN cytotoxicity assay (Figure 1a)

Fluorodeoxyglycose positron emission tomography (FDG PET) identified no body lesions except for an area of increased accumulation lateral to the right jugular vein, which corresponded to an enlarged lymph node, suggesting a nodal metastasis on MRI

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Requires Ongoing Commitment GLP-1 medications are not a one-time solution