Weight loss stems primarily from a reduction in body fat as opposed to lean mass and this weight change is sustained over long-term follow-up [59]
As with nausea, this symptom is likely due to slow gastric emptying
At the beginning of the problem, the median age was 46 years, with 74 % of female patients
Your tolerance for side effects matters
RoB2 examines 5 domains to evaluate the risk of bias in each RCT, whereas ROBINS-I evaluates observational studies in 7 domains to determine the risk of bias as low, some, or high concern
The most commonly reported side effects were gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which were generally mild to moderate and most frequent during the dose-escalation phase