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As well, some people may have allergies or medical conditions that do not allow them to be a good candidate to receive vitamin B12 shots, such as kidney problems, low potassium levels, deficiencies in other vitamins such as iron or folic acid, or just an allergy or sensitivity to vitamin B12 itself

Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine

B12 is an essential vitamin that you can become deficient in, particularly if you follow a restricted or special diet, if youre pregnant or breast feeding, if you suffer from certain health conditions or if you are over a certain age

If you are over age 50, you should aim to eat around 3-5 micrograms per day, while pregnant or breastfeeding women should consume 2-3 micrograms a day

NNMT inhibition Selectively blocks the NNMT enzyme the basis for its metabolic research

What is Vitamin B12 and Why Does It Matter