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These outcomes reportedly emerged without direct suppression of specific cytokines such as TNF, which implies a more regulatory character

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For guidance on preventing negative impact on eyes, see the Effects of rapid reduction in HbA 1c section of the NICE NG242 guideline on diabetic retinopathy, and the MHRA guidance on non-arteritic anterior ischaemic optic neuropathy, both summarised below: When starting treatment likely to result in rapid, substantial HbA 1c reductions, notify the persons ophthalmologist (if the person is attending specialist hospital eye service) so they can assess eyes before treatment begins if they feel this is needed

These are not official guidelines

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Integrating metabolomics domain knowledge with explainable machine learning in atherosclerotic cardiovascular disease classification