The insulin resistance in PCOS might also occur independently of body weight, due to inherited post-receptor defects in insulin signalling that affects metabolism and mitotic pathways, not only in classic insulin target tissues, such as skeletal muscle, liver, and adipose tissue, but also in the non-classical target tissues, such as pituitary and ovary [12, 16]
What it does prove is something more fundamental
But the clinical data tell a nuanced story, and the differences between oral and injectable formulations go beyond patient preference
Thats when many women notice their usual routines stop working
Because oral medications rely on absorption through the digestive system, patients may not absorb the full dose as intended
My doctor taught me to stay on the outside aisles of the store when I go to the grocery store