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Ozempic rose from a 10 th place ranking among the 10 top-selling Part D drugs in 2021, with gross spending of $2.6 billion, to 6 th place in 2022, with spending of $4.6 billion (Figure 2)

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A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis