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In response to nutrients, enteroendocrine L-cells and K-cells produce and release the incretin hormones including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), respectively [2]
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Pediatr.Endocrinol.Diabetes Metab 2010;16(2):78-81
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However, under hyperglycemic conditions, metformin did not affect either Ca 2+ or cAMP responses to incretin signals
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