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[3] Any menstrual changes are therefore most likely mediated through: Metabolic improvements (reduced insulin resistance, weight loss) Changes in adipose tissue and associated hormone production Restoration of hypothalamic-pituitary-ovarian axis function in women with metabolic dysfunction According to NICE guidance (NG28), GLP-1 receptor agonists like semaglutide are recommended for type 2 diabetes when specific criteria are met, typically in combination with other diabetes medications when treatment targets are not achieved
2013 Jun;123(6):2730-6
The same studies can be located independently on PubMed using the CAS number (221231-10-3) or the compound name
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Ocular risks: recent matched cohort studies have suggested a potential association between semaglutide prescriptions and an increased risk of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) (Hazard Ratio 4.28, with inter-study estimates ranging from 4 to 7)
