A daily pill could attract those who prefer to skip weekly injections while still achieving comparable results
Cocaine Only limited clinical evidence is available for GLP-1RAs in cocaine misuse: a small ( N = 13) proof-of-concept trial across 2 days showed that exenatide compared with placebo did not reduce the number of self-administered cocaine infusions 115 , while a case series of 3 individuals with cocaine-use disorder highlighted the feasibility and safety of using the same drug over 6 weeks, although no efficacy measures were reported 116
Reported public examples tied to reduced-price initiatives suggest injectable reduced-tier discussions around the low-to-mid hundreds per month and starter oral tiers around $149/month, but actual costs depend on eligibility, supply, and pharmacy choices
Support was also received via Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) Grant Number JP18dm0207001 (TCS) and a research grant from the RIKEN Center for Brain Science
Flora SJ, Pachauri V
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