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The pharmaceutical industry has made enormous strides in treatingand even curinga wide range of diseases and conditions

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For patients already on venlafaxine at doses 150 mg/day (where NET inhibition becomes clinically relevant), adding an uncharacterized vasopressive modulator creates a monitoring burden that cannot be managed without serial blood pressure measurement

In obese and metabolic-risk populations, higher doses have produced weight loss of up to 15% of baseline body weight

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This process could play a role in anti-aging