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Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab
tetrathiomolybdate (Cu chelation) for copper-catalytic endpoints
The SYNERGY-NASH study, while promising, was a phase 2 trial, and larger phase 3 trials specifically evaluating tirzepatide for MASH are ongoing
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Results were not different when adjusted for BMI
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