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The FDA also cited the company for using unvalidated laboratory testing methods that failed to detect impurities and for inadequate equipment cleaning and cleaning validation practices that increased the risk of cross-contamination between products

While tirzepatide does not directly affect thyroid function, the caloric deficit it produces creates similar metabolic pressure

No significant inhibition of COMT, GNMT, or PNMT observed

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Any off-label, personal, or clinical use is strictly outside the intended scope of supply