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Presentation through MHC-II of native cellular autoantigens or viral EBNA-1 (Fig

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While thats often thought of as a positive outcome for users who say they no longer have the desire to overeat, reduced food intake can lead to nutritional deficiencies if patients arent eating nutrient-rich foods

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Achieving this requires deliberate effort

The SURMOUNT-4 trial showed that when tirzepatide was continued, people maintained and even augmented weight loss, but when it was withdrawn, significant regain followed