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The proposed mechanism of action of these peptides is that they enter the hind-brain from the peripheral bloodstream, and interact directly with GLP-1 receptors in the brain - possibly the parabrachial nucleus (Kanoski et al., 2016)

Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

And fifth, it sets clear benchmarks at weeks 12 and 24 to evaluate whether the current dose is delivering adequate results or needs adjustment

It has been observed that short acting GLP-1 receptor agonists exert their primary hypoglycemic effect by lowering postprandial glucose due to their inhibitory effect on gastric emptying