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Individuals with intestinal disorders like Crohns or Celiac Disease

According to a 2012 review, 29 is the minimum required for complete biological activity.9 The structural difference here means that tesamorelin is a stabilized analog that more closely mimics the hormone on which its based.28 Pharmaceutical status While sermorelin has been discontinued as an FDA-approved drug for growth hormone deficiency, tesamorelin is currently approved as a treatment for HIV-associated lipodystrophy (an accumulation of excess abdominal fat resulting from HIV)

In clinical trials, doses are escalated gradually over several weeks to improve tolerability a process known as dose titration

Mild cases present with tremor and diarrhea

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