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Potential mechanism: By inhibiting the expression of myostatin, negative regulation of muscle growth can be relieved.Diabetes foot ulcer: local application of IGF-1 LR3 gel (0.1 mg/cm ) can accelerate wound closure, and its mechanisms include:Stimulate fibroblast migration and collagen synthesis.Promote the secretion of vascular endothelial growth factor (VEGF) and improve local blood supply
Presented for research literature review only Soares Junior JM et al
Alterations of Oligodendrocyte and Myelin Energy Metabolism in Multiple Sclerosis
High pathological grade might discourage early invasive breast cancer patients who have a pathologic complete response to neoadjuvant systemic therapy from eliminating breast surgery
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It represents a more established regenerative option
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