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dorsalis , Drosophila melanogaster , Aedes aegypti , Homo sapiens , and Mus musculus were aligned using the ESPript 3.0 software ( Statistical analyses and reproducibility To analyse the probability of discrepancies within a specific range, all quantitative data presented in the text and figures were analysed with an unpaired two-tailed t test or Tukeys HSD multiple test in GraphPad Prism 8 software (GraphPad Software, San Diego, CA, USA)