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Method Literature search strategy Google Scholar and PubMed were searched on various dates between December 2016 and March 2017, ending on 15th March 2017 using the following terms, and variants thereof, and all articles discovered were considered for inclusion: (paracetamol OR acetaminophen hepatotoxicity) AND genetic differences/polymorphisms OR children/neonates/young people/paediatric OR older people/elderly/geriatric OR nutritional state/malnutrition OR body weight/low body weight OR alcohol/alcohol-dependence OR drug interactions/potentiation OR liver disease/chronic liver disease/liver failure

Tirzepatide is a medication that activates both GIP and GLP-1 receptors to enhance insulin secretion, reduce appetite, and slow gastric emptying, leading to significant weight loss and improved blood sugar control

After birth, gamma-globin gene expression is suppressed and beta-globin expression is switched on to make adult Hb (Schechter, 2008)

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Using SIM-NLS:GUS, we estimated the site of initiation of endoreduplication and/or length of the MZ