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Poly-L-lysine/hyaluronan nanocarriers as a novel nanosystem for gene delivery

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Triple action mechanism After being absorbed through the nasal mucosa, MT-2 peptide rapidly reaches the hypothalamus via the trigeminal-sympathetic nerve pathway, activates the melanocortin receptor system, and triggers the release of melanocyte-stimulating hormone from the pituitary gland, forming a "neuro-endocrine-skin" cascade reaction

As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning

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However, while the prospects are promising, it is essential to emphasize the need for continued rigorous research to unravel the full spectrum of GHKs capabilities and optimize its efficacy