While many people get enough vitamin B12 from their diet, others may not absorb it efficiently or consume too little
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Capsules are taken orally, typically with water, and are a popular choice for researchers who prefer a non-invasive administration method
Vitamin B12 can then be absorbed into the bloodstream via endocytosis in the distal ileum, or by passive diffusion in the absence of intrinsic factor.2 Pernicious anemia (an autoimmune disease) affects the gastric mucosa, leading to destruction of parietal cells and failure to produce intrinsic factor, resulting in vitamin B12 malabsorption and eventually deficiency
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