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Marcacci, and E

46,47 In addition, the CTD is necessary for contact with negative regulators (MDM2/4) and to induce many posttranslational modifications, such as acetylation, phosphorylation, methylation, and ubiquitination, which adjust its functionality and stability

Some of the limitations of our study are the small sample size, resulting from non-compliance and study drop-out during the rise of the global COVID-19 pandemic