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Laxative Types and Safety Considerations for GLP-1 Users Different laxative classes work through distinct mechanisms and carry different safety profiles when used with GLP-1 medications

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Dietary and lifestyle interventions should be the first-line approach: Increase fibre intake : Aim for 2530 grams of fibre daily through wholegrains, fruits, vegetables, pulses, and seeds

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Animal studies have demonstrated anti-inflammatory effects of GLP-1 receptor agonists in models where weight loss was minimal or absent, suggesting direct pharmacological actions on inflammatory pathways