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Retrieved May 6, 2025, from MedIndia

Mild side effects include pain at the injection site, nausea, skin rashes, or allergic reactions

This dual-mechanism approach enables more pronounced and sustained growth hormone secretion than either peptide administered individually, while preserving the natural pulsatile pattern of growth hormone release that maintains physiological feedback mechanisms

After 28 weeks, the results showed people in each of the treatment groups lost on average: 20 pounds (lb) with a combination treatment of 15 milligrams (mg) phentermine with 92 mg topiramate 13.6 lb with 15 mg phentermine only 14.7 lb for 92 mg topiramate only This suggests that taking the drugs together rather than separately may result in greater weight loss

doi: 10.3389/fcimb.2022.1125463 209 WangY.XueN.WangZ.ZengX.JiN.ChenQ