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Agnihotri, S
The active loss phase is typically 90 days, followed by a maintenance phase
These molecular vulnerabilities have spurred development of targeted therapeutics, with iron chelators (deferiprone), GPX4 stabilizers (Liproxstatin-1), and lipid antioxidant nanoparticles demonstrating 3050% neuroprotection in Parkinsons and Alzheimers models by specifically counteracting the three susceptibility factors
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McEwen BS, Gray J, Nasca C
Osteoarthritis Osteoarthritis is a degenerative joint disease in which chondrocytes, synovial cells, and other joint cells become activated when exposed to an abnormal environment caused by mechanical stress, inflammatory cytokines, or disorganization of the matrix proteins
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