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If the weight-loss benefit of amylin biology comes from the amylin receptor and the tolerability cost comes partly from off-target activity, then a cleaner molecule should in theory separate the two
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Front Neurosci 2019;13:38
BL-B01D1), a first-in-class EGFR-HER3 bispecific antibody-drug conjugate, for patients with EGFR-mutated NSCLC: pooled analysis of phase I and phase II trials
Cell Death Dis 15:859
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