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The individual ingredients have real, documented roles in fat metabolism and liver function

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

In a trial in six healthy women who had experienced an increase in bile cholesterol saturation after starting oral contraceptives, the addition of 600 mg SAMe daily for two cycles of contraceptive use reduced this effect (Di Padova 1984)

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J., Gupta, P