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In 1989, Murphy and colleagues described a neuronal death process resulting from cysteine scarcity, termed oxytosis, which was induced by glutamate inhibiting SLC7A11 (a component of the Xc - system) and shared several characteristics with ferroptosis, including reactive oxygen species (ROS) accumulation and high lipoxygenase enzymatic activity (15, 16)
Palmsten et al., 2020)
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Ikramuddin, S
Murphy JL, Papathakis PC (1993) Hypercholesterolemia in children with cystinosis
& Kivell, B
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