Compared to GIP, which has normal secretion but poor response in patients with T2D, GLP-1, which has low secretion but preserved response, is an important target in the development of antidiabetic drugs
GLP-1 is glucagon-like peptide one, and this is a hormone that is produced by our intestinal cells
Xiong C, Wu J, Ma Y, Li N, Wang X, Li Y, Ding X
For patients taking warfarin, it may be prudent to arrange an extra INR check after initiating Ozempic, after dose changes, or following significant gastrointestinal illness
Frye, B., et al
CI occurred in 405 per 100 patient-years in dulaglutide group and 435 per 100 patient-years in placebo one, but after post-hoc adjustment, the risk of CI in people with T2DM aged 50 years or above who had further cardiovascular risk factors was reduced by 14% of subjects in the dulaglutide arm (HR 0.86, 95% confidence interval 0.790.95