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10.1016/j.drup.2015.02.002 188 van VlietE

What Category 2 Means Category 2 substances are those the FDA has determined may present significant safety risks or lack sufficient evidence to support safe use in humans

Addiction care providers may need to revisit treatment protocols built around behavioral interventions alone

Rohrmann S, Linseisen J

Various stimuli, including telomere dysfunction and oxidative stress, induce cellular senescence through the p53 and Rb proteins, and senescent cells can promote disorders associated with aging or age-related diseases

However, most research connecting acupuncture and hypothyroidism consists of individual case studies, so larger-scale studies are needed to confirm this correlation