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Here's what the research suggests for acute situations: The Evidence-Based Natural Stack Quercetin + Vitamin C + Bromelain is often called the "natural histamine support" combination, and there's good reason: Quercetin supports mast cell stabilization and naturally inhibits release of histamine, leukotrienes, and prostaglandins

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dHL60 cells were treated with 10M BSO or 5M SFN for 16 hours