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Activation of the mevalonate pathway will not only result in an increased cholesterol synthesis, but also in an upregulation of the expression as well as post-translational modifications of small GTPases, which will increase cellular metabolism, proliferation, and migration [111, 113, 114]

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It needs to be however noted that a recent PET study [66] did not replicate Nakatomi et al

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Laboratory accreditation and ISO/IEC 17025