Last month, The New York Times published an article that discusses how this phenomenon is playing out in people using these medications
3.7 Individualized predictive biomarkers for clinical risk stratification Although diverse mechanisms of imatinib-induced gonadotoxicity have been described, clinical translation remains limited by the absence of individualized predictive biomarkers
Ozempic persistently accounted for most of the prescriptions, but prescription fills for Wegovy soared by more than 1,361% between July 2021 and December 2023
The changes are significant enough that other people start commenting
Importantly, these increases did not correlate with serious adverse cardiovascular events in the trial populations, and heart rate typically returned toward baseline levels as treatment continued beyond the dose-escalation phase
For example, if your histamine bucket can hold 4 units before overflowing: 2 units from a mild pollen allergy 2 units from sulfite-induced mast cell degranulation Together, these reach the threshold of 4, triggering symptoms