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RSSDI-ESI Consensus Group
Tirzepatide should always be used under medical supervision
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Doubling the dose instead of splitting it This is the most dangerous mistake
Recent efforts focus on serum biomarkers and predictive models: ( i ) Cytokeratin-18 (CK-18): a marker of hepatocyte apoptosis and necrosis
Most protocols recommend maintaining each dose level for at least 4 weeks to assess tolerance and efficacy before titrating upward
Wageningen, The Netherlands: Wageningen Academic Publishers (2014)
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