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The combination of multiple medications affecting gastrointestinal motility should be carefully evaluated, and patients should be monitored for both efficacy and tolerability

If you experience severe abdominal pain radiating to the back, particularly with nausea or vomiting, stop taking the medication immediately and seek urgent medical attention

Obstructive sleep apnea (OSA): Clinical trials of tirzepatide showed significant improvement of OSA

Published online June 12, 2026 DOI: PDF Supplementary Material 1,799 View 247 Download Original Articles DNMT1 facilitates the progression of metabolic dysfunction-associated steatotic liver disease by impeding transcription mediated by HNF4 and PPAR Hyun Ahm Sohn, Hanyong Go, Tae Hyeon An, Jun Min Lee, Hee-Jin Kim, Keeok Haam, Amal Magdy, Hyo-Jung Jung, Yang-Ji Shin, Hyun Jung Lim, Yujin Jeong, Yejin Bae, Youngae Jung, Seong-Hwan Park, Kyung Chan Park, Myeong Jun Song, Eun-Wie Cho, Eun-Soo Kwon, Jeong Hwan Park, Murim Choi, Geum-Sook Hwang, Dong Hyeon Lee, Kyoung-Jin Oh, Won Kim, Mirang Kim, on behalf of the Innovative Target Exploration of NAFLD (ITEN) Consortium Clin Mol Hepatol 2026;32(3):1201-1224

doi: 10.1016/j.bbr.2020.113094 142 YangYWangBZhongZChenHDingWHoiMPM