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Clinical data demonstrates that gastrointestinal side effects follow a predictable pattern of being most prominent during treatment initiation and dose escalation periods, then declining substantially as the body adapts
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In pathological conditions astroglial cells undergo multiple progressive and/or regressive changes, which can to a significant extent determine the progression and outcome of neurological diseases as discussed below
doi: 10.1016/j.fct.2017.06.044 56
Exclusion criteria subjects with conditions that have so far been identified as modulators of RBC survival must be excluded from participation [89]
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