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We have no other real way of managing obesity other than ineffective instructions about diet and exercise

Clinicians can prescribe GLP-1s off-label for people with BMIs below 27, but insurance rarely picks up the tab

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Primary endpoint was change from baseline in HbA1c

It is unclear whether the pricing agreement will extend to group health plans

Drugs such as ondansetron have been effective for some patients, but they come with their own set of potential side effects and interactions