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Disruption of circadian rhythms contributes to obesity, metabolic disease and cancer, yet how the clock maintains metabolic homeostasis remains limited
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He has worked in health care for more than 20 years
When delta sleep is reduced, as it consistently is in depression, cortisol remains elevated through the night, growth hormone release is blunted, and inflammatory metabolites accumulate in the central nervous system
Cell 180 , 490501.e16 (2020)
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