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The pre-specified primary endpoint, median time to first tolerated meal, was 25.3 hours in the Ipamorelin arm versus 32.6 hours in placebo, p=0.15
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Mar 14 2014;20(10):2433-48
Immunoblotting Cells were washed with PBS and lysed with lysis buffer (150 mM NaCl, 20 mM EDTA, 50 mM Tris-HCl, 0.5% NP-40) containing protease and phosphatase inhibitors
IGF-1 LR3 already provides supraphysiological IGF-1 receptor activation, so adding Tesamorelin + Ipamorelin to stimulate endogenous GH and IGF-1 production offers minimal additional benefit while increasing the risk of receptor desensitization and metabolic dysregulation
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