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Vitamin B12 is crucial for erythropoiesis (red blood cell production), proper digestion and energy utilization
Syringe Units = Desired Dose (mg)Concentration (mg/mL) 100 Example: a 0.5 mg dose at 5 mg/mL = (0.5 5) 100 = 10 units
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Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed
Most published clinical data comes from AOD-9604, not the unmodified fragment
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