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Sings of vitamin B12 deficiency include the following: Megaloblastic anemia is a disorder with fewer red blood cells and larger than normal ones
This can result in a slowed metabolic rate and increased fat storage
Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically
Drug-induced deficiencies (e.g., isoniazid, oral contraceptives)
Iron toxicity can also be the result of excess inflammation, in which case, resolving the source of inflammation can help reduce iron levels