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This distinction is significant: GHK-Cu has a commercial and cosmetic track record that BPC-157 lacks, while BPC-157 has broader systemic preclinical data

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In addition to increased levels of EGT, gliK was demonstrated to exhibit significant sensitivity to H 2 O 2 compared to wild-type (Gallagher et al., 2012), and it is speculated that it may be due to interruption of the gliotoxin biosynthetic pathway following the incorporation of GSH, as GliK catalyzes the enzymatic step directly following GliG-mediated GSH conjugation (Figure 3) (Davis et al., 2011)