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Larger injection volumes create more pressure in the subcutaneous tissue, which can cause more discomfort and a higher chance of lumps or the medication leaking back out

The introduction of oral formulations, such as oral semaglutide approved in 2019, has improved patient convenience and adherence by eliminating the need for injections

Light exposure : UV light damages peptide molecules

Studies in neurodegenerative disease models suggest Dihexa's regenerative capabilities extend to reversing existing damage rather than merely preventing further deterioration

This design choice introduces potential bias, particularly for subjective outcomes, but it reflects the practical reality that these treatments have different injection devices and titration schedules that would make blinding extremely difficult

These findings do not establish general repair of damaged human DNA or prevention of mutations