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In cell culture, FOXO4-DRI induced measurable apoptosis in senescent fibroblasts within 24-48 hours of treatment at effective concentrations (Baar et al., 2017)

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The same phenomenon was observed in the aortic tissues of aging mice after FOXO4-DRI treatment (Figures 6C,D)

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Drach J, Leahy J, Goodacre A, Drach D, Sanchez-Williams G, Weier HU, Pinkel D, Andreeff M

Taking With Coffee or Tea Caffeinated drinks may interfere with nutrient absorption