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So he started TRT

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This is especially true when the headache complaints are not accompanied by the typical features of migraine such as nausea, light/sound sensitivity, and exacerbation upon physical activity (Cutrer 2012)

doi: 10.2174/1567205011310030003 134 NestlerE

In people with severe deficiency, neurological symptoms, or poor absorption, injections are often used first because they bypass the digestive tract and can restore levels more reliably

Apolipoprotein E as a therapeutic target in Alzheimer's disease: a review of basic research and clinical evidence