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Semaglutide diabetic retinopathy is a possibility, although not so much of a concern in those without diabetic retinopathy

doi: 10.1007/s00018-022-04377-0 24 SharpANHeazellAECrockerIPMorG

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The SUSTAIN-6 trial, which tracked over 3,000 patients using semaglutide for diabetes management, reported depression or depressed mood in less than 2% of participants taking the medication versus similar rates in the placebo group

Changes in IC025 values for each GLP-1 RA after gradual expansion of case number