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This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily
2,5 In the Hypertension Optimal Treatment trial of a 5-step intensive BP-lowering regimen, there was a 51% reduction in MACE among the T2DM subpopulation assigned to a diastolic BP target of less than 80 mm Hg
doi: 10.1016/j.knee.2013.01.005 174 FilkovaMLiskovaMHulejovaHHaluzikMGatterovaJPavelkovaAet al
- Direct delivery of functional ingredients through the oral mucosa, which has about 4,000 times the permeability of the epidermis
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