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Nutrients 11(1):pii: E10

Unlike pair-fed rats (rats that ate the same amount of food as the tesofensine-treated rats), the rats treated with tesofensine did not regain their weight, suggesting that tesofensine may increase energy expenditure

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In other words, Rybelsus and Ozempic shouldn't be used for chronic weight management, Novo said

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Individuals with uncontrolled diabetes must also be monitored closely, as GH can impact insulin sensitivity