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University of Michigan.

Priority was given to peer-reviewed experimental, translational, and clinical studies that directly addressed thyroid dysfunctionrelated neuropsychiatric outcomes, as well as plant-derived nutritional interventions with clear mechanistic relevance to oxidative stress, neuroinflammation, neurotransmission, or bloodbrain barrier regulation

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Preliminary cardiac studies have also explored the use of recombinant human T4 following severe ST-segment elevation myocardial infarctions (STEMI), with early pilot data suggesting the intervention is feasible, safe, and potentially capable of improving left ventricular ejection fractions by more than 50% in specific cohorts six months post-infarction