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In colorectal cancer, SCFAs, especially butyrate, function as anti-inflammatory metabolites and histone deacetylate (HDAC) inhibitors, resulting in the suppression of cancer progression (72)

Telomere shortening with cell-division cycles is a key marker of cellular replicative senescence

doi: 10.1111/liv.15930 89

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Accordingly, we found that B6 MZB had a higher endoplasmic reticulum (ER)/Golgi ratio than B6 FoB as measured by their greater staining intensity of ER-tracker and giantin (Supplementary Fig